Vitamin D Toxicity
نویسندگان
چکیده
منابع مشابه
Toxicity of Vitamin D
In 1999, Vieth indirectly asked the medical community to produce any evidence 10,000 units of vitamin D a day was toxic, saying, “Throughout my preparation of this review, I was amazed at the lack of evidence supporting statements about the toxicity of moderate doses of vitamin D”. He added, “If there is published evidence of toxicity in adults from an intake of 250ug (10,000 IU)/d, and that is...
متن کاملPharmacokinetics of vitamin D toxicity.
Although researchers first identified the fat-soluble vitamin cholecalciferol almost a century ago and studies have now largely elucidated the transcriptional mechanism of action of its hormonal form, 1alpha,25-dihydroxyvitamin D(3) [1alpha,25(OH)(2)D(3)], we know surprisingly little about mechanisms of vitamin D toxicity. The lipophilic nature of vitamin D explains its adipose tissue distribut...
متن کاملHypercalcemic crisis due to vitamin D toxicity.
1. What should be included in the differential diagnosis of hypercalcemia? Are the patient’s laboratory findings consistent with her reported use of vitamin supplements? 2. What role does vitamin D play in Ca2+ homeostasis? 3. Other than excess nutritional supplement use, what are additional causes of vitamin D toxicity? 4. What are the symptoms of vitamin D toxicity? How should vitamin D toxic...
متن کاملAcute Vitamin D Toxicity in an Infant
We report vitamin D toxicity in an infant following consecutive administration use of a large dose of vitamin D, causing symptomatic hypercalcemia, which was successfully managed with injectable calcitonin. However, the child developed bilateral medullary nephrocalcinosis which persisted 42 mon after the initial episode.
متن کاملVitamin D: Deficiency, Sufficiency and Toxicity
The plethora of vitamin D studies over the recent years highlight the pleomorphic effects of vitamin D outside its conventional role in calcium and bone homeostasis. Vitamin D deficiency, though common and known, still faces several challenges among the medical community in terms of proper diagnosis and correction. In this review, the different levels of vitamin D and its clinical implications ...
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ژورنال
عنوان ژورنال: Brazilian Journal of Nephrology
سال: 2020
ISSN: 2175-8239,0101-2800
DOI: 10.1590/2175-8239-jbn-2019-0192